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First Roundup Trial Since Supreme Court Ruling Opens in St. Louis

Published October 5, 2026

A jury in St. Louis is hearing the first Roundup cancer trial since the U.S. Supreme Court sided with Bayer in June. Opening statements began September 29, 2026, in a Missouri state court case brought by three women who used the weedkiller regularly and later developed non-Hodgkin lymphoma, according to Reuters and other reports.

Who is suing and what they claim

The plaintiffs are Theresa Aretino, Cynthia Fernandez, and Betty Larkin. Fernandez died before trial, and her claims are proceeding on her behalf. None of the three is part of Bayer's proposed class settlement. Their lawyers argue that Monsanto, the Bayer unit that makes Roundup, did not adequately test the product before selling it and that Roundup was defectively designed and too dangerous to be sold.

Bayer maintains that decades of research show glyphosate, Roundup's active ingredient, is safe and does not cause cancer. It also argues that the Supreme Court's decision rules out design-defect claims like these.

Why this trial is a test case

The Supreme Court's 7-2 ruling on June 25, 2026, in Monsanto v. Durnell held that federal pesticide law blocks state-law claims that Roundup's label should have carried a cancer warning (see our coverage of the ruling). Failure-to-warn claims had been the backbone of most Roundup lawsuits. This trial is focused on design defect and testing instead, theories the Supreme Court did not directly address. The verdict will offer an early read on whether those claims can still win in front of a jury.

The settlement still has no ruling

The trial is happening while Bayer's proposed $7.25 billion class settlement, which aims to resolve current and future Roundup claims, waits on a decision. Missouri Judge Timothy Boyer held the final approval hearing on September 14 and had not ruled as of early October. Objecting law firms argue the payouts undervalue claims. Roughly 65,000 Roundup cases remain pending in U.S. courts.

If you or a family member were diagnosed with non-Hodgkin lymphoma after regular Roundup exposure, see Atumio's Roundup case page for a free eligibility review, or start your case review directly.

Sources: This article was written by Atumio based on news reporting, and is not legal advice. For more detail, see the original coverage: "Bayer Faces Trial Test of Remaining Roundup Claims After Supreme Court Win" (Claims Journal (Reuters), September 30, 2026), "Openings Heard In Closely Watched Post-Durnell Monsanto Roundup Trial" (CVN, September 2026), and "Bayer Faces New Missouri Roundup Trial While $7.25 Billion Settlement Awaits Judge's Ruling" (Global Agriculture, October 3, 2026).